From motivation to action: functional interface between the limbic system and the motor system.

Contents 1. Introduction 2. Historical background 3. Evidence implicating limbic and related structures in the initiation of motor responses 4. The motor control of behavior 5. Limbic-motor interface: a tentative model 6. Experimental evidence in support of the model 6.1. First component: Limbic projections to ventral tegmental area 6.1.1. Anatomical and electrophysiological evidence 6.1.2. Behavioral evidence 6.2. Second component: Projections from ventral tegmental area to nucleus aecumbens 6.2.h Anatomical and electrophysiological evidence 6.2.2. Behavioral evidence 6.3. Third component: Projections from nucleus accumbens to globus pallidus 6.3.1. Anatomical and electrophysiological evidence 6.3.2. Behavioral evidence 7. The limbic-motor interface in relation to current views concerning response initiation 8. Suggested experiments to further investigate the model 9. Summary Acknowledgements References Note added in proof